En los estudios se utilizaron cultivos de células de glioma (un tumor cerebral muy agresivo) al que sometieron a dos tratamientos por separado, por un lado a la ausencia de nutrientes y por el otro al suministro de THC que potencia y activa una acción más destructiva. El tratamiento aumenta los niveles de los lípidos dihydroceramide que después de un tiempo provocan la muerte de la célula infectada a la que desestabiliza en forma importante.


En estudios ‘in vitro’ como en tumores generados en ratones la manipulación de los niveles de estos lípidos puede ser una estrategia para activar una autofagia que conduce a la muerte de las células tumorales, lo que reduciría el crecimiento tumoral. Velasco dijo que “Estas observaciones pueden contribuir a sentar las bases para el desarrollo de nuevas terapias antitumorales basadas en la activación de la muerte a través de la autofagia”, y ayudar a comprender el mecanismo de acción de los cannabinoides en células tumorales.

Buenas noticias que indican una vez mas los avances respecto a esta difícil enfermedad.

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